在上海成年人中,EAT-Lancet饮食坚持和发生的2型糖尿病之间的关联:前性队列研究
Xiaoli Xu1, Genming Zhao2, Xing Liu2
1Minhang District Center for Disease Control and Prevention (Minhang District Institute of Health Supervision), Shanghai, 201101, China.
坚持EAT-Lancet饮食显著降低了上海成年人2型糖尿病 (T2D) 风险. 由EAT-Lancet指数 (ELDI) 表示的更高的坚持与减少T2D发病率相关,强调中国糖尿病预防的可持续饮食.
科学领域:
- 营养流行病学 营养流行病学
- 公共卫生 营养 公共卫生 营养
- 预防慢性疾病 预防慢性疾病
背景情况:
- 中国的2型糖尿病 (T2D) 率上升与西方化的饮食有关.
- 需要通过饮食分析制定有效的T2D预防策略.
研究的目的:
- 评估EAT-Lancet饮食对上海成年人T2D预防的健康益处.
- 调查EAT-Lancet饮食的坚持与T2D风险之间的关联.
主要方法:
- 利用了来自上海郊区成年人队列和生物库 (SSACB) 的数据,共有29507名参与者.
- 使用半定量性食物频率问卷 (FFQ) 评估EAT-Lancet饮食的坚持,以计算EAT-Lancet指数 (ELDI).
- 使用Cox比例危险模型和限制立方 (RCS) 来分析T2D发病率和剂量反应关系.
主要成果:
- 随访时间中位数为5.6年,发现了977例T2D病例.
- 较高的ELDI得分 (≥33) 与显著降低的T2D风险相关 (HR:0.70;95%CI:0.52,0.95).
- 每增加1个单位的ELDI,T2D风险降低2% (HR:0.98;95%CI:0.96,0.99),并观察到非线性相关性.
结论:
- 对EAT-Lancet饮食的更大坚持与上海T2D的可能性降低有关.
- 可持续的饮食模式对于预防中国人口糖尿病至关重要.
- 在中国城市,EAT-Lancet饮食显示出作为T2D预防策略的前景.
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