德国皮肤淋巴瘤发病率和死亡率的最新趋势
Khodr Cheikh El Najjarine1, Hiltraud Kajüter2, Ina Wellmann2
1Department of Dermatology HELIOS Klinikum Krefeld, Academic Teaching Hospital of the University of Aachen, Krefeld, Germany.
概括
这项研究发现,德国的原发性皮肤淋巴瘤 (PCL) 发病率高于此前的预期,生存率有所提高,特别是对于塞萨里综合征患者. 数据涵盖了2008年至2021年的数据.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 初级皮肤淋巴瘤 (PCL) 包括皮肤T细胞淋巴瘤 (CTCL) 和皮肤B细胞淋巴瘤 (CBCL).
- 了解PCL发生率和存活率对于患者护理和公共卫生倡议至关重要.
研究的目的:
- 确定德国原发性皮肤淋巴瘤 (PCL) 的发病率和存活率.
- 分析PCL数据,包括成人和儿科人口.
主要方法:
- 利用来自北莱-威斯特法利亚癌症登记处 (2008-2021) 的数据,覆盖1800万个人.
- 计算了PCL,CTCL和CBCL的年龄标准化发病率和相对存活率统计.
主要成果:
- 包括3853例新诊断的PCL病例:69.5%CTCL,24.9%CBCL.
- PCL发病率为每百万人/年10.8,随着时间的推移,CTCL和CBCL的趋势越来越大.
- 整体五年PCL存活率为89%;塞萨里综合征存活率为53%.
结论:
- 这是德国PCL最大的基于人群的研究,涵盖所有年龄组.
- 现在的PCL发病率比以前报告的要高,现在有生存数据.
- 患有塞萨里综合征的患者的生存概率明显高于以前所理解的.
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