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Updated: Jan 8, 2026

Assaying the Kinase Activity of LRRK2 in vitro
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Published on: January 18, 2012

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在零星帕金森病中,LRRK2作为潜在的疾病修饰标

Anthony E Lang1, Robert A Hauser2, Lorraine V Kalia1,3,4

  • 1Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital and Edmond J. Safra Program in Parkinson Disease, University of Toronto, Toronto, Ontario, Canada.

Movement disorders : official journal of the Movement Disorder Society
|December 13, 2025
PubMed
概括

氨酸丰富的重复激酶2 (LRRK2) 抑制在帕金森病 (PD) 中显示出前景. 向LRRK2可能会改善 lysosomal 功能,并减少在零星PD和LRRK2-链接PD中的神经退行.

关键词:
α-synuclein; LRRK2; 溶酶体; 帕金森病

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