监禁前在滥用或依赖毒品的囚犯中使用精神活性物质:来自OPPIDUM计划的数据
Zeinab Abbas1, Clémence Lacroix2, Elisabeth Jouve2
1Centre d'Addictovigilance, Centre Hospitalier Universitaire, Montpellier, France.
Fundamental & clinical pharmacology
|December 13, 2025
概括
这项研究发现,静脉注射药物使用,非法获取物质以及特定类型的毒品,如海洛因/速度球和可卡因/可卡因,与囚犯中更高的精神活性物质滥用和依赖率有关. 然而,阿片类药物替代治疗与较低的发病率有关.
科学领域:
- 成研究研究成研究
- 犯罪学 犯罪学
- 公共卫生 公共卫生
背景情况:
- 评估监狱人口中精神活性物质 (PAS) 滥用和依赖的患病率对于有针对性的干预至关重要.
- 该 OPPIDUM 计划提供了有关在惩戒设施中的个人中物质使用模式的宝贵数据.
研究的目的:
- 确定监狱囚犯中精神活性物质 (PAS) 依赖和滥用的流行率.
- 在这个人群中确定与增加PAS滥用和依赖风险相关的因素.
主要方法:
- 利用了来自国家OPPIDUM计划 (2013-2022) 的数据,这是对寻求成治疗的人进行的横截面研究.
- 监狱囚犯报告简单的PAS使用与那些有虐待/依赖问题的囚犯进行了比较,收集了监禁前一周的PAS使用数据.
主要成果:
- 大麻 (52.8%),可卡因/crack (28.6%),二 (23.1%),和海洛因 (14.8%) 是最常用的PAS.
- 静脉注射使用,非法获取PAS,使用海洛因/速度球或可卡因/可卡因显著增加了滥用/依赖的几率.
- 阿片类药物替代治疗 (OST) 与滥用/依赖的可能性降低有关.
结论:
- 虽然承认自我报告数据和潜在的样本偏差等局限性,但该研究强调了囚犯中PAS使用的高流行率.
- 识别风险因素,如特定的药物使用模式和施用途径,对于有效的预防和管理策略至关重要.
- 阿片类药物替代治疗在减轻监狱人口中药物滥用和依赖方面显示出有希望.
相关概念视频
Drug Dependence
1.6K
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
1.6K
Drug Abuse and Addiction: Pharmacological Phenomena
1.1K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.1K
Substance Use Disorders Affecting Sleep
366
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
366
Opioid Analgesics: Synthetic and Semisynthetic Opioids
878
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
878
The Stanford Prison Experiment
24.5K
The famous and controversial Stanford Prison Experiment, conducted by social psychologist Philip Zimbardo and his colleagues at Stanford University, demonstrated the power of social roles, social norms, and scripts.
24.5K
Healthcare Agencies II
1.0K
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources,...
1.0K


