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Updated: Jan 8, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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通过TRPV4介导的机械感知调节了内皮转移到介质细胞的转变:对动脉样硬化的影响

Pritha Mukherjee1, Karunakaran R Sankaran1, Mohammad Imran Khan1

  • 1Department of Nutrition and Food Science, University of Maryland, College Park, Maryland, USA.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|December 13, 2025
PubMed
概括

瞬态受体潜在化物4 (TRPV4) 通道通过感知矩阵刚度来调节内皮细胞到介质细胞的过渡 (EndMT). 抑制TRPV4可以防止EndMT,为心血管疾病提供潜在的治疗点.

关键词:
甲状腺内皮细胞 甲状腺内皮细胞机械感知机械感知机器拉力力显微镜 拉力力显微镜暂时的受体潜力 瓦尼洛伊德4

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