预测心理辅助疗法治疗反应的预测因素:系统性审查
Grace Viljoen1,2, Henrik Walter1, Antonia Bendau1
1Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Department of Psychiatry and Neurosciences CCM, Berlin, Germany.
Journal of psychopharmacology (Oxford, England)
|December 13, 2025
概括
急性迷幻体验的强度,特别是神秘类型的体验 (MTE),是迷幻辅助治疗 (PAT) 中治疗反应的最常见预测因素. 未来的研究应该调查更多的预测因素并提高一致性.
科学领域:
- 精神病学和心理学 精神病学和心理学
- 神经科学是一个神经科学.
背景情况:
- 迷幻辅助疗法 (PAT) 对各种心理健康状况显示出显著的疗效.
- 患者的变化导致对PAT的反应不同.
- 识别反应预测因素对于优化治疗结果至关重要.
研究的目的:
- 系统地审查预测心理治疗辅助疗法的治疗反应的因素.
- 综合有关PAT疗效患者特异性和治疗相关预测指标的证据.
主要方法:
- 从研究开始到2024年3月进行了全面的系统文献搜索.
- 包括的研究集中在心理健康治疗中对经典迷幻药物反应的预测因素上.
- 分析涵盖了各种患者群体和诊断类别.
主要成果:
- 包括54项研究,检查了诸如抑郁症,焦虑症,PTSD和物质使用障碍等疾病的预测因素.
- 急性迷幻体验的强度,特别是神秘类型的体验 (MTE),成为最常见的预测因素.
- 诸如设置,设置和剂量等因素影响了MTEs,影响了治疗反应.
结论:
- 在迷幻辅助治疗期间的神秘类型体验 (MTE) 与治疗反应密切相关.
- 需要进一步的研究来探索更广泛的预测因素.
- 为未来的试验,建议加强方法严谨性,并包括更长的随访期.
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