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相关概念视频

Imprinting01:22

Imprinting

Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...

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相关实验视频

Updated: Jun 30, 2026

Polymer Microarrays for High Throughput Discovery of Biomaterials
13:37

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Published on: January 25, 2012

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基于分子打印的厚度编码悬挂阵列

Ziling Ye1, Junjie Zheng1, Zhijie Pan1

  • 1School of Mechanical Engineering and Automation, Fuzhou University, Fuzhou 350000, China.

ACS sensors
|December 13, 2025
PubMed
概括
此摘要是机器生成的。

我们开发了一种新的厚度编码微芯片阵列,用于多重检测,提供440个不同的代码. 这种高通量平台为各种诊断应用提供了敏感的生物标志物检测.

关键词:
分子印记是一种分子印记.多重检测检测多重检测检测频谱域相位显微镜的相位显微镜.一个悬挂阵列的悬挂阵列.编码的厚度编码.

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相关实验视频

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科学领域:

  • 生物标志物发现发现
  • 纳米技术 纳米技术
  • 分析化学 分析化学

背景情况:

  • 多复合同时检测需要具有高容量的先进编码技术.
  • 现有的方法往往缺乏必要的编码能力,或者价格过高.

研究的目的:

  • 介绍一款用于高通量多重检测的新型悬挂阵列平台.
  • 开发一个厚度编码的,MIP功能化的石英微芯片阵列,配有自定义解码系统.

主要方法:

  • 使用简单的一工艺制造MIP功能化的石英微芯片阵列.
  • 开发一个定制的厚度光解码系统,具有微米级分辨率.
  • 定量多重测定用于IgG检测.

主要成果:

  • 在一毫米的动态范围内实现了440个具有微米级分辨率的独特代码.
  • 人类,老鼠和子IgG的检测极限为7.6,7.9和15μg mL−1.
  • 在定量多重测定中表现出高灵敏度,选择性和时间稳定性.

结论:

  • 基于MIP的厚度编码微芯片阵列平台可实现强大的,高通量生物标记器检测.
  • 这种具有成本效益的平台适用于环境监测,食品安全和临床诊断.