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Updated: Jan 8, 2026

Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer
11:46

Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy Transfer

Published on: May 26, 2014

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从鱼类到四足动物的脊椎动物中追踪Foxp2蛋白质的分子进化:对多Q通道变异,结构变化和相互作用网络的洞察

Ahmet Efe Köseoğlu1, Gülsüm Deniz Köseoğlu2, Buminhan Özgültekin3

  • 1COMED Therapeutics, Malta Life Sciences Park, San Gwann, Malta.

Computational biology and chemistry
|December 13, 2025
PubMed
概括

这项研究揭示了Foxp2基因对于言语和运动技能至关重要,它已经进化出了独特的特征,如人类,牛和鱼中缺席的多Q重复,在鱼类中缺席. 这突显了进化联系和潜在的疾病相关性.

关键词:
科莱坎特 (Coelacanth) 是一个类动物.特定于血统的插入.维护Poly-Q和PTM的保护结构性遗传学 结构性遗传学脊椎动物的Foxp2蛋白质是什么

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