对心理干预措施的变化进行范围审查,以治疗与生命结束相关的心理痛苦
Sarah Kratina1, Carol Strike2, Robert Schwartz3
1Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, 155 College Street, 4th fl, Toronto, Ontario, Canada, M5T 3M6.
Social science & medicine (1982)
|December 13, 2025
概括
关于治疗生命终点痛苦的迷幻干预的研究表明,物质和治疗方法的多样性很大. 这种多样性凸显了用于息治疗的迷幻药研究的探索阶段,其结果和机制各不相同.
科学领域:
- 心理药理学 心理药理学
- 精神病学是一个精神病学.
- 抚慰性护理是一种缓解性护理.
背景情况:
- 迷幻药物显示出减轻生命末期心理痛苦的希望,但政策限制仍然存在.
- 现有的审查不充分涵盖了临终关怀中各种类型的迷幻药物和治疗方法的范围.
研究的目的:
- 探索对面临危及生命的疾病和生命末期心理痛苦的个人的迷幻干预研究中的多样性.
- 识别和理解为生命末期人口的迷幻研究中各种物质,干预措施和结果的范围.
主要方法:
- 使用了一个范围审查框架 (Arksey & O'Malley,2005) 和用于范围审查的PRISMA扩展.
- 数据提取侧重于干预细节,迷幻物质,参与者特征,结果和理论化机制.
主要成果:
- 确定了59项涉及6种迷幻药物治疗生命终结问题的研究,主要使用案例研究设计.
- 干预措施各不相同,包括单独给药,准备/给药/整合,以及与心理治疗一起给药.
- 具有挑战性的经历是常见的,经常被认为是治疗性的;结果跨越了生物心理社会精神领域. 在超过40%的研究中报告了神经生物学,心理和精神机制.
结论:
- 目前关于用于终身心理痛苦的迷幻药物的研究显示了研究设计和治疗模式的相当多样性.
- 这种变化反映了该领域的新生和探索性质,多样化的理论基础,以及潜在的治疗应用的丰富景观.
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