在患有轻度/中度和重度慢性静脉疾病的妇女中,对外周组织输液和小腿功能进行比较,并对症状强度进行比较
Tiago da Silva Nogueira1, Maria Luiza Vieira Carvalho2, Rafaela Pedrosa3
1Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
概括
患有严重慢性静脉疾病 (CVD) 的女性表现出更差的静脉排空和增加的反流. 较高的体重指数可能与心血管疾病患者的症状严重程度相关.
科学领域:
- 血管医学 血管医学
- 生理学 生理学 生理学
- 生物医学工程 生物医学工程
背景情况:
- 慢性静脉疾病 (CVD) 影响了相当一部分人口,影响了生活质量.
- 了解症状严重程度,小腿肌功能和组织输液之间的关系对于有效的管理至关重要.
- 周围组织输液和小腿肌肉功能是心血管疾病中循环健康的关键指标.
研究的目的:
- 为了比较患有慢性静脉疾病 (CVD) 的妇女的小腿肌肉功能和外周组织输液.
- 在心血管疾病群体中区分轻度/中度和重度症状组.
- 调查症状强度与生理参数之间的关联.
主要方法:
- 一项涉及女性心血管疾病 (C1 - C3阶段) 的横截面研究.
- 使用视觉模拟尺度 (VAS) 评估症状严重程度,将参与者分为轻度/中度 (I组) 和严重 (II组) 组.
- 使用近红外光谱法 (NIRS) 测量周围组织 perfusion 与静脉封闭和运动囊造影;通过高跟抬起测试 (HRT) 评估小腿肌肉功能.
主要成果:
- 55名女性参加了这次活动,其中30名女性参加了I组,25名女性参加了II组.
- 第二组 (严重症状) 的残留体积分数 (RVF_HHb) 和保留分数 (RF_HHb) 显著较高,表明静脉排泄较差和反流增加 (p<0.05).
- 在II组观察到更高的体重指数 (BMI) (p=0.003),而小腿肌功能 (HRT_T,HRT_N) 在两组之间没有显著差异.
结论:
- 与症状较轻的女性相比,患有严重心血管疾病症状的女性经历了静脉排空受损和反流升高.
- 心血管疾病的症状严重程度增加可能与更高的BMI有关.
- 虽然输液受到了影响,但根据高跟升高测试测量的小腿肌肉功能,在这个队列中,根据症状严重程度,没有显著差异.
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