中国成年人的相对脂肪量和心血管风险:全国前性队列研究
Fang Wang1, Xingliang Li1, Long Wang1
1Department of Cardiology, China-Japan Friendship Hospital, Beijing, China.
Nutrition journal
|December 13, 2025
概括
较高的相对脂肪量 (RFM) 独立地预测了中国成年人的心血管疾病 (CVD). 这种脂肪指数可以提高心血管疾病风险预测,超越传统的因素,为预防提供了一种实际的工具.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 人类测量学 人类测量学.
背景情况:
- 相对脂肪量 (RFM) 和心血管疾病 (CVD) 之间的关联在中国人群中未得到充分研究.
- 中国成年人具有独特的脂肪性模式,可能会影响RFM-CVD关系.
研究的目的:
- 评估RFM对中国成年人发生心血管疾病的预测价值.
- 评估RFM在提高心血管疾病风险分层方面的实用性.
主要方法:
- 来自中国健康与退休长度研究 (2011-2020) 的7027名中国成年人 (≥45岁) 的分析.
- 使用性别特异方程计算RFM;用于RFM-CVD关联的考克斯回归.
- 使用AUC,NRI和IDI对增量预测值的评估.
主要成果:
- 增加的RFM与更高的心血管疾病风险相关 (HR=1.03每单位增加).
- 最高的RFM四分位数显示,心血管疾病风险比最低的46%高 (HR=1.46).
- 超越弗雷明汉风险因素,RFM改善了心血管疾病预测 (AUC为0.640对比0.634).
结论:
- 较高的RFM是中国成年人发生心血管疾病的独立预测因素.
- RFM增强了传统的心血管疾病风险分层.
- RFM是预防心血管疾病的实际人体指数,特别是在资源有限的环境中.
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