腰与身高的比作为脏鼻脂肪的非侵入性标志物:基于MRI的队列研究
Diego Moriconi1, Miikka-Juhani Honka2,3, Ekaterina Saukko4
1Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
International journal of obesity (2005)
|December 14, 2025
概括
腰与身高的比率 (WHtR) 和其他腰部测量比BMI更好地预测脏鼻脂肪 (RSF). RSF百分比 (RSF%) 独立地预测功能 (eGFR).
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心血管健康 心血管健康
- 肥胖问题研究研究
背景情况:
- 脏鼻腔脂肪 (RSF) 是一种与高血压和慢性病相关的宫外脂肪储存.
- 体重指数 (BMI) 是一种常见的,但潜在地有限的脂肪度量.
研究的目的:
- 评估各种脂肪指数是否比BMI更准确地预测脏鼻腔脂肪 (RSF).
- 评估RSF,RSF百分比 (RSF%) 和功能 (EGFR) 之间的关系.
主要方法:
- 磁共振成像 (MRI) 评估了严重肥胖和瘦肉志愿者的RSF和RSF%.
- 多变量回归分析检查了肥胖指数 (包括BRI,WHtR,腰围) 和RSF/RSF%之间的关联,并根据年龄,性别和BMI进行调整.
- 分析了RSF和肥胖度的变化,并分析了腹腔外科手术后的情况.
主要成果:
- 腰与身高的比率 (WHtR),身体圆度指数 (BRI) 和腰围显示出与RSF最强的关联,独立于BMI.
- 在多变量分析中,WHtR是唯一与RSF%有显著关联的指标.
- 在多变量分析中,RSF%与估计的淋巴球过率 (eGFR) 独立相关,而RSF则没有.
结论:
- 包括腰围在内的肥胖度指标与RSF有显著的关联,提供了超越BMI的见解.
- 比RSF,RSF%是功能 (eGFR) 的一个更强的预测指标.
- 无论是RSF还是RSF%,都为了解代谢和脏健康提供了补充信息.
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