血压变化:从预测标记物到干预目标 - - 打破高血压目标器官损伤的恶性循环
Ruiqin Luo1, Ying Huang1, Yanjun Leng1
1Department of Cardiology, Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine, Shenzhen, Guangdong, Peoples's Republic of China.
血压变化 (BPV) 显著推动高血压目标器官损伤 (TOD) 和心血管事件. 控制BPV以及平均血压对于预防TOD和改善患者的治疗结果至关重要.
科学领域:
- 心血管医学 心血管医学
- 高血压研究 高血压研究
- 临床药理学 临床药理学
背景情况:
- 高血压目标器官损伤 (TOD) 是心血管事件和死亡的主要原因.
- 尽管控制了平均血压 (BP),但一些患者的TOD进展仍在继续.
- 血压变化 (BPV) 越来越被认为是 TOD 的独立风险因素.
研究的目的:
- 系统地审查将BPV与TOD联系起来的流行病学证据.
- 阐明BPV有助于TOD病变的机制.
- 讨论精确管理策略,以减轻高血压中的BPV.
主要方法:
- 对BPV和TOD的流行病学研究进行系统审查.
- 分析机械路径,包括内皮功能障碍,炎症和动脉硬.
- 审查BPV专注的管理策略的近期进展.
主要成果:
- BPV是一个独立的预测器和TOD的积极贡献者.
- 这种BPV会加剧高血压-动脉样硬化循环.
- 内皮功能障碍,炎症和动脉硬是关键的调解途径.
结论:
- 高血压的临床管理应整合BPV控制,而不仅仅是平均BP.
- 针对BPV对于破坏TOD恶性循环至关重要.
- 对血压管理的综合方法对于预防心血管事件至关重要.
更多相关视频
07:51Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
相关概念视频
Errors occurring during blood pressure monitoring
Several factors...
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Factors affecting Blood pressure
Physiological Factors:
