兄弟姐妹状态和晚年痴呆症风险
Juwen Wang1,2, Hui Liu1,2, Wencheng Zhang3
1Department of Sociology, Purdue University, West Lafayette, Indiana, United States.
概括
晚年有活着的兄弟姐妹与降低痴呆风险有关,特别是在女性身上. 相反,失去两个或两个以上的兄弟姐妹会增加老年人的痴呆症发病率.
科学领域:
- 老年学是一门学科.
- 认知神经学 认知神经学
- 社会流行病学 社会流行病学
背景情况:
- 社会联系对于老化中的认知健康至关重要.
- 兄弟姐妹关系在晚年认知衰退中的作用仍然未被充分探索.
研究的目的:
- 调查兄弟姐妹地位与老年人痴呆风险之间的关联.
- 探索这种关系中潜在的性别差异.
主要方法:
- 利用了来自健康和退休研究 (2000-2018) 的数据.
- 分析了17,474名在基线时50岁以上的参与者.
- 采用离散时间危险回归模型,考虑兄弟姐妹的存在,数量和兄弟姐妹的损失.
主要成果:
- 活着的兄弟姐妹与更低的痴呆症发病率有关,特别是在女性中.
- 经历失去两个或两个以上的兄弟姐妹与痴呆症风险增加相关.
- 在活着的兄弟姐妹的数量或兄弟姐妹的性别组成和痴呆风险之间没有发现显著的关联.
结论:
- 兄弟姐妹关系是老年人认知健康的一个重要,未被充分研究的因素.
- 保持兄弟姐妹的联系可能是预防认知衰退的保护因素.
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