血清水平作为登革热严重程度的标记:一项临床观察性研究
Rajesh Deshwal1, Abhisek Sharma2
1Professor, Department of Emergency Medicine, Pacific Medical College and Hospital, Udaipur, Rajasthan, India, Corresponding Author.
The Journal of the Association of Physicians of India
|December 14, 2025
概括
低血症是登革热中常见的电解质干扰,是疾病严重程度的重要预测因素. 监测血清水平可以帮助早期检测和管理严重登革热病例.
科学领域:
- * 传染病 传染病
- * 临床生物化学 * 临床生物化学
- * 流行病学 流行病学
背景情况:
- *登革热是全球重要的健康问题.
- *电解质失衡,特别是低血症,在登革热患者中很常见.
- * 在登革热中缺血的预后值未得到充分利用.
研究的目的:
- * 调查纠正的血清水平与登革热严重程度之间的关联.
- * 为了确定缺血症是否可以预测严重的登革热结果.
主要方法:
- *前性观察性研究,涉及210名成年登革热患者.
- * 血清水平在入院后24小时内测量,并对白蛋白进行校正.
- *严重程度使用世界卫生组织 (WHO) 2009年标准进行分类;统计分析包括相关性和后勤回归.
主要成果:
- * 平均纠正的血清水平随着登革热严重程度的增加而显著下降 (p < 0.001).
- * 低血症 (<8.5 mg/dL) 在91.3%的严重登革热病例中存在.
- *较低的水平与较高的血红素,较低的血小板数和较长的住院时间相关;低血症独立预测严重登革热 (aOR:3.94).
结论:
- * 低血是常见的发现,也是严重登革热的重要独立预测因素.
- * 血清度测量是一种简单,具有成本效益的预后工具.
- *利用血清水平可以改善登革热流行地区的早期分拣和管理策略.
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