间皮瘤发病率的全球模式和趋势:一个回顾性横截面研究
Leiwen Fu1, Ke Liu1, Yang Liu1
1Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China.
Lung cancer (Amsterdam, Netherlands)
|December 14, 2025
概括
间皮瘤发病率显示出全球差异,欧洲承担了最大的负担. 公共卫生工作至关重要,以减少对石棉的暴露和疾病,特别是在越来越多的间皮瘤率的地区.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 间皮瘤是一种罕见的,攻击性的癌症,主要与接触石棉有关.
- 它主要影响有职业石棉接触史的老年人.
研究的目的:
- 估计2022年全球间皮瘤发病率和死亡率.
- 分析中瘤发病率的长期趋势.
- 调查间皮瘤负担的地理和社会经济差异.
主要方法:
- 使用GLOBOCAN 2022数据库进行2022年的估计.
- 五大洲的就业癌症发病率 (CI5) 数据库用于长期趋势分析.
- 计算了年龄标准化发病率 (ASIR) 并使用Joinpoint回归来评估趋势.
主要成果:
- 在2022年,全球估计有30633例间皮瘤病例 (ASIR:0.28/100,000).
- 欧洲占全球病例 (48.1%) 和死亡人数 (48.4%) 的最大份额.
- 在克罗地亚,韩国,斯洛文尼亚的男性和加拿大的女性中,发病率增加;在其他几个地区,发病率下降.
结论:
- 间皮瘤带来了重大的全球健康挑战,具有地理和社会经济差异.
- 持续的公共卫生倡议对于消除接触石棉和减轻疾病负担至关重要.
- 需要针对性干预,在经历中瘤发病率上升的地区.
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