用多年生麦草进行营养干预通过调节脂质代谢来缓解肝功能障碍:从肠肝轴的见解
Muhammad Arslan Asif1, Zeshan Zulfiqar1, Bahar E Mustafa2
1Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, Henan, China.
Poultry science
|December 14, 2025
概括
多年生麦草是一种食纤维,通过改善肠道健康和脂质代谢来保护免受脂肪肝疾病的影响. 这种天然料添加剂增强肝功能,减少的疾病指标.
科学领域:
- 动物营养 动物营养
- 肝病学 肝病学是一种肝病学.
- 肠道微生物组研究研究
背景情况:
- 在家禽中,缩饮食可能导致肝硬化症 (脂肪肝疾病).
- 众所周知,食纤维对肠道健康和脂质代谢有积极的影响.
- 多年生杂草被探索为其潜在的肝保护作用的天然纤维来源.
研究的目的:
- 为了研究多年生麦草在食缩食中的肝保护作用.
- 评估多年生麦草对子肠道微生物群,脂质代谢和肝脏健康的影响.
主要方法:
- 幼被食缩饮食,其中包括多年生麦草的含量不同 (0%,30%,50%).
- 分析了肠道微生物的多样性和组成.
- 评估了脂原和脂肪酸氧化基因表达.
- 评估了肝脏脂质积累,炎症和抗氧化剂潜力.
- 进行了新陈代谢分析.
主要成果:
- 多年生瑞草增加了肠道微生物的多样性,有利于短链脂肪酸生产者,同时减少纤维化相关的细菌.
- 在饮食中加入多年生麦草抑制了脂原基因表达和增强脂肪酸氧化.
- 组织病理学证实减少了肥胖症,肝细胞膨胀和炎症,非酒精性脂肪肝疾病活动得分较低.
- 代谢学揭示了减少的脂毒代谢物和和脂肪酸,增加的欧米茄-3脂肪酸和植物代谢物.
结论:
- 多年生草在中起到多层次的肝保护作用.
- 它调节肠肝交叉通话,增强氧化还原平衡,并恢复脂质平衡.
- 多年生麦草代表了一种有希望的,具有成本效益的营养策略,用于预防家禽脂肪肝疾病.
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