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mTOR信号通路在质母细胞瘤及其干细胞中的复杂作用

Austin B Carpenter1, Ariel Sacknovitz1, Simon Hanft1

  • 1Department of Neurosurgery, New York Medical College/Westchester Medical Center, Valhalla, 10595, New York, USA.

Advances in biological regulation
|December 14, 2025
PubMed
概括

猛素 (mTOR) 途径失调的哺乳动物目标驱动着质母细胞瘤 (GBM) 的生长和复发. 双重mTOR抑制剂在向GBM及其癌症干细胞方面表现有前途,提供了新的治疗策略.

关键词:
质母细胞瘤 (glioblastoma) 是一个干细胞是一种干细胞.在mTOROR中使用mTOR.在 mTORC1 的情况下,mTORC1 是 mTORC1.在mTORC2癌症中,mTORC2是癌症.

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