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Updated: Jul 9, 2026

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基于激素的设计和优化tecovirimat衍生品作为强大的抗病毒药物对抗水病毒病毒

Yuanguang Chen1, Sumei Yang2, Xingyu Zhou3

  • 1Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, Shenzhen Grubbs Institute and Medi-X Pingshan, Southern University of Science and Technology, Shenzhen, 518000, China; Shenzhen AntiV Pharma Co., Ltd., Shenzhen, Guangdong, 518081, China.

European journal of medicinal chemistry
|December 14, 2025
PubMed
概括

研究人员开发了新型的tecovirimat衍生物来对抗麻疹病毒 (MPXV) 爆发. 一个有前途的化合物,C12,在临床前研究中显示出强大的抗病毒活性,良好的生物可用性和低毒性.

关键词:
分子动力学分子动力学麻疹病毒的病毒.这是一种P37蛋白质.德科维里马特衍生品的衍生品

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