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Updated: Jan 8, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
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被MHC I类分子捕获的脂联体经历了动态的构造变化,影响了它们的抗原强度

Daisuke Morita1, Toshiki Fujii2, Shinsuke Inuki3

  • 1Laboratory of Cell Regulation, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan.

The Journal of biological chemistry
|December 14, 2025
PubMed
概括

主要组织相容性复合体I类蛋白质存在N-myristoylated脂. 这项研究揭示了脂形状决定了T细胞受体结合和抗原强度,解释了相似的表位素如何引起不同的免疫反应.

关键词:
这种T细胞受体是T细胞受体.在X射线晶体学.抗原呈现的呈现方式.免疫学 免疫学 免疫学这是一种脂抗原抗原.主要的组织相容性复合物I类.蛋白质的里斯托基化.

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