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Updated: Jan 8, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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在光滑肌中RSAD2-YTHDF1轴的激活会通过细胞间线粒体转移引起炎症性肠病

Wen-Di Zhang1,2,3, Dan-Dan Zhang1,2,3, Xu Wang4

  • 1Department of Biochemistry and Molecular Biology, College of Basic Medicine, Hebei Medical University, Shijiazhuang, China.

Nature communications
|December 14, 2025
PubMed
概括

缺少SM22α的光滑肌细胞会因RSAD2-介导的线粒体功能障碍和铁亡引起的大肠炎. 向RSAD2-YTHDF1通路可能为性结肠炎 (UC) 提供一种新的治疗策略.

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