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Updated: Jan 8, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

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甘油聚合物结合致病性IgM自身抗体,并将它们拉入单核细胞系统中进行降解

Butrint Aliu1, Delphine Demeestere2, Lijuan Pang2,3

  • 1Molecular Pharmacy, Department of Pharmaceutical Sciences, University of Basel, 4056, Basel, Switzerland. butrint.aliu@hotmail.com.

Scientific reports
|December 14, 2025
PubMed
概括

糖聚物PPSGG有效地消除了抗HNK-1IgM自身抗体在抗髓相关的糖蛋白神经病变. 这种抗原特异性治疗通过清除引起疾病的抗体而没有毒性的治疗潜力.

关键词:
抗MAG神经病变是一种神经病变.抗原特异性葡萄糖聚合物.具有神经学意义的单克隆性胃病变.单核细胞系统是一个单核细胞系统.垃圾搜索器的受体是什么?

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