在水生和陆生物种中评估循环和线性挥发性甲基素的生物积累潜力:使用生物积累评估工具进行全面分析
Jaeshin Kim1, Debra A McNett1, Sami Belkhiria1
1Product Safety Research, Core R&D, The Dow Chemical Company, Midland, MI, 48647USA.
Integrated environmental assessment and management
|December 14, 2025
概括
挥发性甲基酸盐 (VMS) 在水生和陆生物种中具有较低的生物积聚潜力. 对50项研究的审查表明,VMS通常不会在食物网中生物放大,这表明环境风险有限.
科学领域:
- 环境科学 环境科学
- 生态毒理学 生态毒理学
- 化学品风险评估 化学品风险评估
背景情况:
- 挥发性甲基酸盐 (VMS) 是一组循环和线性酸盐化合物,用于各种工业和消费品.
- 人们对VMS在环境区和生物群中的潜在生物积累和生物放大存在担忧.
- 了解VMS生物积累对于评估其生态影响和为监管决策提供信息至关重要.
研究的目的:
- 综合分析水生和陆生物种中三种周期性 (D4,D5,D6) 和五种线性 (L2,L3,L4,L5,L6) VMS的生物积累.
- 评估已发表文献和实验室报告中的生物积累因子 (BAF),生物度因子 (BCF) 和生物放大因子 (BMF) 数据.
- 确定VMS在不同生态系统中的总体生物积累潜力和热带转移.
主要方法:
- 对50篇发表的文章和实验室报告进行了系统审查.
- 使用生物积累评估工具使用量化证据权重 (qWoE) 方法来评估178个生物积累值.
- 分析了来自水生 (82%) 和陆生 (18%) 物种的数据,包括BCF,BAF,BMF和热量放大因子 (TMF) 的值.
主要成果:
- 观察到水生生物中VMS的BCF和BAF值存在相当大的变化,其中一些超过了监管值.
- 非生物积累的频率 (BCF或BAF<2000) 为D6,L2,L5和L6的≥50%.
- 实验室和实地BMF值一般为<1,表明通过饮食摄入的生物积累潜力较低. 水生食物网中的TMF大多为<1,但具有很高的变异性.
- 对于陆地物种 (老鼠),BMF在37°C时为<1,呼吸道排泄是主要的途径. D4在陆地食物网中显示了食物稀释,而D5和D6没有生物放大.
结论:
- 总体证据 (≥71%) 表明循环和线性VMS通常不会在水生物种中生物积累,而饮食吸收是主要途径.
- 尽管存在一些变化,并且在某些情况下超过监管值,但低BMF和TMF值表明生物放大潜力有限.
- 对于陆地物种,VMS表现出较低的生物积累潜力,主要通过呼吸消除,D4显示有机稀释.
- TMF值的不确定性突出了环境因素的影响和潜在的抽样偏差,需要在不同的环境环境中进行进一步的研究.
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