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患有原发性副甲状腺症手术的患者的与健康相关的生活质量:患者报告的结果衡量结果

Lily N Trinh^1,2, Okenwa C Okose^1,3, Amr H Abdelhamid-Ahmed¹

¹Division of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.

|December 15, 2025

概括

原发性甲状腺功能障碍症 (PHPT) 的手术显著改善了患者的健康相关生活质量 (HRQL). 患者报告说身体和精神健康改善,并减少了对甲状腺切除术后的担忧.

科学领域:

内分泌学在内分泌学.
手术瘤学手术瘤学
生活质量研究研究生命质量研究

背景情况:

原发性甲状腺功能障碍症 (PHPT) 通常用甲状腺切除术来治疗,这种手术可以提高与健康有关的生活质量 (HRQL).
评估患者报告的结果对于了解PHPT治疗的全部影响至关重要.

研究的目的:

从患者的角度来看,评估PHPT副甲状腺切除术后一般和疾病特定HRQL的变化.
量化PHPT手术干预后患者福祉的改善情况.

主要方法:

一组44名为PHPT进行甲状腺切除术的患者完成了经过验证的患者报告结果测量 (PROM).
调查包括"担忧"调查,语音障碍指数-10 (VHI-10) 和患者报告结果测量信息系统全球-10 (PROMIS).
术前和术后使用PROM来追踪HRQL的变化.

主要成果:

手术后评估显示,患者对甲状腺癌,手术和相关问题的担忧显著减少 (p < 0.05).
PROMIS评估显示,手术后身体健康,精神健康和一般健康领域的统计学上显著改善 (p < 0.05).
该研究包括44名患者 (39名女性,平均年龄65岁),其中73%患有单一腺瘤,27%患有多腺体疾病.

结论:

副甲状腺切除术导致PHPT患者与健康相关的生活质量的显著改善.
手术治疗有效地解决了PHPT患者的疾病特异性问题和一般健康问题.

关键词:

在这种情况下,Prom是Prom.副甲状腺腺体是什么意思质量质量质量质量质量质量.手术手术手术手术手术手术手术担心担心担心担心

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