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双COX-2/5-LOX抑制通过新型甲状腺衍生物:从分子建模到体外验证

Alice Romeo1, Silvia Pezzola2, Francesca Valentini2

  • 1Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00133, Rome, Italy.

Chembiochem : a European journal of chemical biology
|December 15, 2025
PubMed
概括

新型醇衍生物被设计为双环氧化酶-2/5-氧化酶 (COX-2/5-LOX) 抑制剂. 这些化合物显示出作为更安全的抗炎替代品的潜力,特定的衍生物显示出对COX-2和5-LOX标的高活性.

关键词:
5 - 洛克斯 5 - 洛克斯在COX‐2中,二氧化碳排放量为2.分子对接的分子对接.分子动力学分子动力学乙醇衍生品的甲醇衍生品

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