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通过突变对Mycobacterium结核病Methionyl-tRNA合成酶的影响来识别明显的基质和中间识别

Shivani Thakur1, Rukmankesh Mehra1,2

  • 1Department of Chemistry, Indian Institute of Technology Bhilai, Durg, Chhattisgarh, India.

Proteins
|December 15, 2025
PubMed
概括

耐药结核病需要新的点. 研究人员在Mycobacterium tuberculosis (Mtb) 中探索了Methionyl-tRNA合成酶 (MetRS),揭示了突变如何影响其功能和基质结合,这对药物开发至关重要.

关键词:
结核病菌菌菌的结核病菌的结核病菌.甲基尼尔-tRNA结合酶是什么分子动力学模拟模拟突变是一种突变.基质特异性 基质特异性结核病是一种肺结核病.

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