精神疾病和心房动风险:瑞典基于人口的队列研究
Xingbo Mo1,2, Imre Janszky1,3, Hui Wang1,4
1Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
European journal of preventive cardiology
|December 15, 2025
概括
几种精神疾病 (PD) 与患上心房动 (AF) 的风险增加有关. 这项大规模的研究强调了心理健康状况和心律问题之间的联系.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 前庭动 (AF) 是一个越来越严重的公共卫生问题,原因不明.
- 现有的关于心理健康和AF之间联系的研究,特别是除了抑郁和焦虑之外的其他精神疾病 (PDs),是有限的.
研究的目的:
- 调查广泛的精神疾病 (PDs) 与患有发生性心房 (AF) 的风险之间的关联.
主要方法:
- 利用瑞典医疗出生登记处的数据,从2001年到2023年跟踪3,815,546名父母.
- 采用Cox比例危险和灵活的参数生存模型来评估PD和AF风险.
- 纳入兄弟姐妹的比较,以控制潜在的家庭混因素.
主要成果:
- 在随访期间,超过80万名参与者至少有一次PD,超过21万人在随访期间发展出AF.
- 总体PD和特定PD亚型与发生AF的风险增加显著相关.
- PD和AF风险之间的关联在随访初期最强,但随着时间的推移而持续.
结论:
- 这项研究确立了多种PD和发展AF的风险增加之间的联系.
- 需要进一步的研究来证实这些发现,并阐明潜在的生物和环境机制.
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