高血压检测的横截面模型的预测变量和诊断性能:系统审查
Víctor Juan Vera-Ponce1, Fiorella E Zuzunaga-Montoya2, Jhosmer Ballena-Caicedo1
1Facultad de Medicina (FAMED), Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM), Amazonas, Perú.
Frontiers in cardiovascular medicine
|December 15, 2025
概括
这项研究审查了高血压的诊断模型,发现年龄和BMI等简单的临床因素是有效的. 需要对代表性不足的人群进行更多的研究,以改善全球高血压检测.
科学领域:
- 心脏病学和公共卫生
- 流行病学和生物统计学
背景情况:
- 全球有13亿人患有高血压,其中许多人未被诊断,因此需要有效的诊断工具.
- 及时检测高血压对于控制心血管疾病风险至关重要.
研究的目的:
- 系统地识别和评估全球成年人高血压诊断的横截面预测模型.
- 评估现有的高血压诊断模型的性能和预测因素.
主要方法:
- 按照PRISMA和TRIPOD指导方针进行系统审查,从2000年至2024年搜索主要数据库 (MEDLINE/PubMed,Scopus,科学网络,EMBASE).
- 包括开发或验证成人高血压预测模型的观察性研究.
- 使用PROBAST工具进行偏差风险评估.
主要成果:
- 包括8项研究,主要来自亚洲人群.
- 模型显示出良好的区分能力 (AUC 0.70-0.89),在后勤回归和机器学习方面表现相似.
- 关键预测因素包括年龄,BMI,性别/性别和糖尿病;实验室生物标志物提供了最小的改善.
- 对于拉丁美洲人口的预测模型,存在一个重要的研究差距.
结论:
- 截面预测模型,特别是更简单的临床模型,对于高血压检测是有效的.
- 未来的模型应该专注于代表性不足的人群,纳入健康的社会决定因素,并可用于资源有限的环境.
相关概念视频
Hypertension III: Clinical Manifestations and Diagnostic Studies
442
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
442
Errors occurring during blood pressure monitoring
1.3K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
1.3K
Hypertension and Regulation of Blood Pressure
3.6K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.6K
Hypertension I: Introduction
668
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
668
Sensitivity, Specificity, and Predicted Value
1.2K
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Sensitivity is the...
1.2K
Pre-Procedural Guidelines for Assessing Blood Pressure
790
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
790


