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喉癌患者中的抑郁症:一项回顾性队列研究
Sandhya Ganesan1,2, Sharwani Kota1,3, Sana Smaoui4
1The Division of Otolaryngology - Head & Neck Surgery The George Washington University School of Medicine and Health Sciences Washington DC USA.
Laryngoscope investigative otolaryngology
|December 15, 2025
概括
喉癌患者患抑郁症的风险更高,尤其是年轻患者,社会经济弱势患者和接受手术的患者. 治疗后的副作用显著增加了抑郁症的风险.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 喉癌治疗经常导致说话和吞问题,可能导致抑郁症.
- 抑郁症会对喉癌幸存者的治疗结果和患者存活率产生负面影响.
研究的目的:
- 为了确定抑郁症在喉癌患者的患病率.
- 为了确定与这种人群中抑郁症相关的风险因素.
主要方法:
- 利用来自TriNetX研究网络的ICD-10代码来识别93018名喉癌患者.
- 患者按治疗类型,年龄,社会经济地位 (SES) 和治疗后的副作用分层.
- 分析了这些因素对抑郁症发展的影响,控制了癌症的阶段.
主要成果:
- 与一般头癌患者相比,喉癌患者患抑郁症的风险高出15%.
- 年轻的患者 (70岁以下),有SES风险因素的患者 (2.67倍风险),以及接受手术的患者 (1.54倍风险) 的抑郁风险明显更高.
- 长期并发症,如消化不良和异口症增加了7.62%的抑郁风险 (p < 0.01).
结论:
- 喉癌患者患有治疗后抑郁症的风险特别高.
- 对查和支持性护理的进一步研究对于改善心理健康结果至关重要.
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