胸痛 拉塔诺普罗斯 布诺德 0.024% 管理: 一个案例报告
Zubair Edakkavil1, Misbah Fazlani1, Ahmer Longi1
1Internal Medicine, Mediclinic Welcare Hospital, Dubai, ARE.
Cureus
|December 15, 2025
概括
一位患者在开始使用拉坦诺普洛斯布诺德眼药治疗青光瘤后出现了胸痛. 症状在停止治疗后消失,突出显示需要对局部绿眼治疗的心血管安全性进行监测.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 拉塔诺普罗斯0.024%是一个氧化捐赠的前列腺素类似物,用于开角玻璃眼和眼睛高血压.
- 虽然通常是安全的,但有报道罕见的系统性不良反应.
研究的目的:
- 报告一个用拉坦普洛斯治疗的患者患有胸痛的病例.
- 突出局部玻璃眼药物的系统性心血管不良影响的潜力.
主要方法:
- 一个63岁的男性病例报告,患有正常张力玻璃眼.
- 开始使用拉塔诺普罗斯眼药滴.
- 综合性心脏病评估,包括心电图,生物标志物,心声回声和压力测试.
- 在停止药物治疗后观察症状的消失.
主要成果:
- 患者在开始服用拉坦诺普罗斯布诺德后不久就出现了胸痛,喉干燥和胃灼热.
- 心脏病学评估没有什么显著的.
- 停用眼滴后12小时内,胸痛完全消失.
结论:
- 局部使用拉坦普洛布诺德可能会导致系统性心血管不良反应,如胸痛.
- 在开始局部格劳科马药物治疗时,对非典型的全身症状进行临床警至关重要.
- 需要进一步研究前列腺素类 analog 的心血管安全性.
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