1p36删除综合征中的牙异常:一个案例报告
Faris A Alotaibi1, Mohammed K Alotaibi1, Tarfa N Moharib2
1Department of Pediatric Dentistry, King Saud Medical City, Riyadh, SAU.
Cureus
|December 15, 2025
概括
这项案例研究突出显示了一名患有1p36删除综合征 (1p36DS) 的儿童的独特牙表现,包括犬类生殖和超数切口. 早期的牙科干预改善了功能和信心.
科学领域:
- 牙科 牙科是指牙科的专业.
- 遗传学 是一个遗传学.
- 儿科医学 儿科医学
背景情况:
- 1p36删除综合征 (1p36DS) 是一种罕见的染色体疾病,与各种面和全身异常有关.
- 牙异常在1p36DS中很常见,但之前还没有记录过狗生殖和超数切口器的特定组合.
研究的目的:
- 报告1p36DS.DS.患者的新型牙表现.
- 强调多学科方法和早期牙科干预在1p36DS.患者管理中的重要性.
主要方法:
- 一个9岁的沙特女孩的临床和放射性牙科评估1p36DS.
- 综合性治疗包括预防性护理,修复性治疗,外科切除多余的牙,以及拦截式正牙.
- 涉及儿科牙医和其他专家的多学科合作.
主要成果:
- 该患者出现了多种病变,阴道,内闭,所有主要和永久性犬的产生 (除了一个保留的主要犬外),以及两个超数的切刀 (mesiodens).
- 执行的治疗计划导致改善了牙美学,功能和心理社会信心.
- 这一介绍扩展了1p36DS. 的已知牙科表型谱.
结论:
- 1p36DS的管理需要多学科的方法,因为复杂的异常.
- 儿童牙医在早期检测,预防性护理和及时干预方面发挥着至关重要的作用,以改善生活质量.
- 常规的牙科成像和警对于识别罕见的染色体疾病和指导综合护理至关重要.
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