在以西班牙裔为主的人口中,骨质疏松症管理方面的差距
Rachel L Moraes Dantas1, Jenivia Sekar1, Sudhagar Thangarasu2
1Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, USA.
Cureus
|December 15, 2025
概括
这项研究发现,骨质疏松症和骨质疏松症的护理存在显著差距,特别是在西班牙裔社区. 许多患有这些疾病的妇女没有评估骨折风险或适当治疗,这表明需要改进管理策略.
科学领域:
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 骨质疏松症是一种普遍的疾病,有确定的管理准则,但它经常没有被诊断和治疗.
- 诊断不足和治疗不足导致严重的发病率和医疗保健成本.
研究的目的:
- 确定特定社区的骨质疏松症和骨质疏松症风险因素.
- 评估使用骨折风险评估工具 (FRAX) 的使用情况.
- 评估骨质疏松和骨质疏松妇女的治疗差距.
主要方法:
- 对387名被诊断患有骨质疏松症或骨质疏松症的50岁以上妇女进行了回顾性图表审查.
- 收集的数据包括人口统计,病史 (骨折,吸烟,类固醇使用,BMI,并发症) 和护理质量指标 (FRAX文档,药物使用,DXA扫描频率).
- 分析的重点是风险因素,FRAX评分文档,药物处方率和补充剂使用.
主要成果:
- 大多数387名女性 (58.1%) 患有骨质疏松症,83%是西班牙裔或拉丁裔.
- 以前的骨折是最常见的风险因素 (46%).
- 只有37.5%的人有记录的FRAX得分,近三分之一的骨质疏松症或高风险骨质疏松症患者没有接受药物治疗. 维生素D和补充剂的含量很低 (40.6%).
结论:
- 在被研究的西班牙裔社区内,骨质疏松症和骨质疏松症的评估和管理存在显著的护理差距.
- 不充分利用FRAX工具和不充分的药理治疗突出显示了临床干预的领域.
- 改善查,风险评估和治疗坚持是减少骨折风险的关键.
相关概念视频
01:29Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
01:40Bone Remodeling
40.2K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.2K
01:31Osteoclasts in Bone Remodeling
3.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.8K
01:15Drug Dosing: Geriatric Patients
209
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
209
01:31Essential Minerals for Bone Health
5.9K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
5.9K
01:25Role of Vitamins in Maintaining Bone Health
5.0K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.0K