穿皮内镜腰椎切除术后的Modic变化和腰椎椎间板的复发之间的关联:一个元分析
Xianfeng Li1, Honghong Ren2, Lipeng Peng1
1Department of Orthopedics, The Second People's Hospital of Yibin, Yibin, Sichuan, China.
Frontiers in surgery
|December 15, 2025
概括
手术前的Modic变化增加了穿皮内镜腰椎间盘切除术 (PELD) 后腰椎间盘 (LDH) 复发的风险. 患有Modic变化的患者面临着早期和晚期的复发机会明显更高.
科学领域:
- 整形外科 整形外科 整形外科
- 神经外科 神经外科
- 放射学 放射学是一门学科.
背景情况:
- 腰椎间盘 (LDH) 是一种常见的疾病,需要手术干预.
- 穿皮内镜腰椎切除术 (PELD) 是LDH的一种微创治疗方法.
- 磁力共振成像上的模态变化与退行性磁盘疾病有关,可能会影响手术结果.
研究的目的:
- 调查手术前Modik变化与LDH复发之间的关联.
- 为了确定Modic变化是否会影响PELD后早期或晚期复发的风险.
主要方法:
- 一个系统的审查和对PubMed,科学网络,EMBASE和CNKI的研究进行元分析.
- 包括27项研究,包括10116名接受PELD的患者.
- 用95%置信区间 (CI) 分析复发率和几率比率 (ORs),并按复发时间分析子组.
主要成果:
- 与没有 (7.44%) 患者相比,有Modic变化的患者 (16.41%) 的整体复发率更高 (7.44%).
- 手术前的Modic变化与增加LDH复发风险显著相关 (OR = 2.96).
- 这种关联在早期和晚期复发中保持一致,在Modic类型I和II/III之间没有显著差异.
结论:
- 手术前的Modik变化是PELD后手术后LDH复发的重要风险因素.
- 莫迪克变化的存在与早期和晚期复发的可能性更高有关.
- 临床医生在评估用PELD治疗的LDH患者复发风险时应考虑Modic变化.
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