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一种携带IL-12的瘤性简单疹病毒,用于治疗临床前质母细胞瘤

Joseph W Jackson1, Bonnie L Hall2, Chaim Sneiderman3

  • 1Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN 37920, USA.

Molecular therapy. Oncology
|December 15, 2025
PubMed
概括

在瘤性简单疹病毒 (oHSV) 工程与介质素-12 (IL-12) 显著改善了质母细胞瘤模型的生存率. 这种疗法通过增加瘤微环境中的巨细胞和T细胞来增强抗瘤免疫反应.

关键词:
在GBMGBMGBMGBMGBM在HSV中,它是HSV.癌症 癌症 癌症 癌症 癌症免疫疗法 免疫疗法一个单一的集体化.

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