Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Protein Folding01:25

Protein Folding

10.9K
Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
10.9K
Protein Folding01:22

Protein Folding

125.8K
Overview
125.8K
Protein and Protein Structure02:15

Protein and Protein Structure

86.6K
Proteins are one of the most abundant organic molecules in living systems and have the most diverse range of functions of all macromolecules. Proteins may be structural, regulatory, contractile, or protective. They may serve in transport, storage, or membranes; or they may be toxins or enzymes. Their structures, like their functions, vary greatly. They are all, however, amino acid polymers arranged in a linear sequence.
A protein's shape is critical to its function. For example, an enzyme...
86.6K
Protein Organization01:24

Protein Organization

9.0K
Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....
9.0K
Protein Organization01:13

Protein Organization

155.5K
Overview
155.5K
Globular Proteins01:27

Globular Proteins

9.7K
In organisms, proteins are the most abundant macromolecules. They act as the building blocks of life and play various crucial roles in the body. Proteins can be broadly classified into two distinct subtypes based on their shape and solubilities: globular proteins and fibrous proteins.
Globular proteins serve many important physiological functions, such as acting as enzymes, cellular messengers, and molecular transporters. These roles often require the proteins to be soluble in the aqueous...
9.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

COVID-19 Vaccines and the Virtues.

Public health ethics·2023
Same author

The emergence of the postgenomic gene.

European journal for philosophy of science·2022
查看所有相关文章

相关实验视频

Updated: Jan 8, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

69.7K

"形状就是一切:关于蛋白质的功能":作者

Francesca Bellazzi1

  • 1Department of Philosophy, Leverhulme Trust Early Career Fellow, Durham University, 50 Old Elvet, Durham, DH1 3HN UK.

Biology & philosophy
|December 15, 2025
PubMed
概括

这项研究通过将它们与原生结构和进化的生物过程联系起来来定义蛋白质功能. 它阐明了蛋白质结构与其特定的生物化学功能之间的关系.

科学领域:

  • 生物化学 生物化学
  • 分子生物学分子生物学
  • 科学哲学的科学哲学

背景情况:

  • 蛋白质是生命的基础,但它们的功能往往是隐含的定义.
  • 了解蛋白质功能对于生物和生物化学研究至关重要.
  • 现有的定义缺乏蛋白质结构和功能之间的明确联系.

研究的目的:

  • 为了解决蛋白质功能定义的隐含性质.
  • 提出一个框架来表征蛋白质功能.
  • 研究原生蛋白质结构在定义生化功能中的作用.

主要方法:

  • 分析生物化学功能的现有定义.
  • 检查蛋白质结构和功能之间的关系.
  • 血红蛋白和晶体的案例研究,以评估拟议的帐户.

主要成果:

  • 蛋白质功能是与原生蛋白质结构的特定结构性质 (化学和几何) 相关的配置.
  • 这些功能有助于进化的生物过程.
  • 原生结构是表征蛋白质功能的关键元素.

结论:

关键词:
生物化学类型 生物化学类型蛋白质 蛋白质 蛋白质结构 结构 是一个结构.没有了,没有了,没有了.

更多相关视频

RNA Secondary Structure Prediction Using High-throughput SHAPE
13:42

RNA Secondary Structure Prediction Using High-throughput SHAPE

Published on: May 31, 2013

32.1K
Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes
11:58

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes

Published on: January 30, 2019

8.7K

相关实验视频

Last Updated: Jan 8, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
16:41

A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

69.7K
RNA Secondary Structure Prediction Using High-throughput SHAPE
13:42

RNA Secondary Structure Prediction Using High-throughput SHAPE

Published on: May 31, 2013

32.1K
Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes
11:58

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes

Published on: January 30, 2019

8.7K
  • 蛋白质功能的正确表征必须考虑原生结构.
  • 拟议的账户为了解蛋白质功能提供了一个强大的框架.
  • 这种方法阐明了蛋白质研究中的"结构问题"和"功能问题".