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Updated: Jan 8, 2026

Using Scaffold Liposomes to Reconstitute Lipid-proximal Protein-protein Interactions In Vitro
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酸酶的小分子激活剂PP2A重塑脚手架PR65结构动力学以促进全酶组装

Sema Z Yilmaz1, Anupam Banerjee2,3, Satyaki Saha2,3

  • 1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.

bioRxiv : the preprint server for biology
|December 15, 2025
PubMed
概括

蛋白酸酶2A (PP2A) 的小分子激活剂与PR65亚单元结合,稳定了扩展的构造. 这种结合机制对于激活PP2A至关重要,为癌症治疗提供了潜在的策略.

关键词:
坦德姆重复蛋白质可以重复蛋白质.激活器绑定绑定 激活器绑定绑定网站 绑定网站结合诱导的形状变化分子动力学模拟,分子动力学模拟

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