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Updated: Jan 8, 2026

Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection
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Spatial Profiling of Protein and RNA Expression in Tissue: An Approach to Fine-Tune Virtual Microdissection

Published on: July 6, 2022

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拉里斯能够在空间转录组学中进行准确和高效的连接体和受体相互作用分析

Min Dai1,2, Tivadar Török3, Dawei Sun3,4

  • 1Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

bioRxiv : the preprint server for biology
|December 15, 2025
PubMed
概括

我们开发了LARIS,这是一种用于分析空间转录组学数据的新计算方法,以了解细胞通信. 拉里斯精确地绘制了组织中的联体受体相互作用,揭示了细胞在发育和疾病中如何相互信号.

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MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as A Novel Detection and Quantification Method

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Ligand Binding Sites02:40

Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
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