相关实验视频

Updated: Jan 8, 2026

Detection of Copy Number Alterations Using Single Cell Sequencing
09:45

Detection of Copy Number Alterations Using Single Cell Sequencing

Published on: February 17, 2017

12.1K

基于序列与图形对齐的副本号码调用使用网络流量配方

Hugo Magalhães, Jonas Weber, Gunnar W Klau

    bioRxiv : the preprint server for biology
    |December 15, 2025
    PubMed
    概括

    弗洛科通过使用网络流公式来提高基因组图的复制数 (CN) 调用精度. 这种方法通过提供更一致的CN预测来增强疾病关联研究和基因组组合验证.

    更多相关视频

    Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons07:59

    Author Spotlight: Alignment of Synchronized Time-Series Data Using the Characterizing Loss of Cell Cycle Synchrony Model for Cross-Experiment Comparisons

    Published on: June 9, 2023

    1.8K
    Detection of Rare Mutations in CtDNA Using Next Generation Sequencing11:11

    Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

    Published on: August 24, 2017

    17.3K

    相关概念视频

    Comparing Copy Number Variations and SNPs02:26

    Comparing Copy Number Variations and SNPs

    Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
    Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...
    18.5K
    Signal Flow Graphs01:18

    Signal Flow Graphs

    Signal-flow graphs offer a streamlined and intuitive approach to representing control systems, providing an alternative to traditional block diagrams. These graphs use branches to symbolize systems and nodes to represent signals, effectively illustrating the relationships and interactions within the system.
    In a signal-flow graph, branches denote the system's transfer functions, while nodes represent the signals. The direction of signal flow is indicated by arrows, with the corresponding...
    580
    Next-generation Sequencing03:00

    Next-generation Sequencing

    The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
    Next-Generation Sequencing Methods
    Although all next-generation methods use different technologies, they all share a set of standard features....
    97.6K
    The Power Flow Problem and Solution01:26

    The Power Flow Problem and Solution

    Power flow problem analysis is fundamental for determining real and reactive power flows in network components, such as transmission lines, transformers, and loads. The power system's single-line diagram provides data on the bus, transmission line, and transformer. Each bus k in the system is characterized by four key variables: voltage magnitude Vk​, phase angle δk​, real power Pk​, and reactive power Qk​. Two of these four variables are inputs, while the power flow program computes...
    781
    Network Function of a Circuit01:25

    Network Function of a Circuit

    Frequency response analysis in electrical circuits provides vital insights into a circuit's behavior as the frequency of the input signal changes. The transfer function, a mathematical tool, is instrumental in understanding this behavior. It defines the relationship between phasor output and input and comes in four types: voltage gain, current gain, transfer impedance, and transfer admittance. The critical components of the transfer function are the poles and zeros.
    599
    Genome Copying Errors02:46

    Genome Copying Errors

    DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their  survival. Therefore, the copying errors are checked and repaired at three levels.
    5.0K