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Updated: Jan 8, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
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Published on: July 29, 2007

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失调的乳酸代谢与ALS遗传风险因素协同作用,加速运动衰退

Shweta Tendulkar1, Tong Wu2, Amy Strickland2

  • 1Department of Developmental Biology, Washington University School of Medicine, St. Louis, 63110, United States.

bioRxiv : the preprint server for biology
|December 15, 2025
PubMed
概括

降低乳酸脱酶B (LDHB) 功能会损害神经肌肉连接和运动行为. 这种LDHB缺乏与ALS遗传风险因素相互作用,突显了乳酸代谢在神经退行症中的作用.

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