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Updated: Jan 8, 2026

Author Spotlight: Unveiling the Role of SNF2L in Replication Fork Stability and Genome Duplication
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Published on: August 23, 2024

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在BRCA1-RAD51轴调节SCAI/REV3依赖复制叉维护维护

Chloe Unterseher, Hiroshi Tsuchida, Rosevalentine Bosire

    bioRxiv : the preprint server for biology
    |December 15, 2025
    PubMed
    概括

    BRCA1促进了停滞的复制分叉恢复,独立于分叉保护,需要SCAI和REV3进行DNA修复和重新启动. 这些因素的丧失导致基因组不稳定和细胞死亡.

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