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失调的TFEB-自-溶酶体通路将急性COVID-19免疫病理与长期COVID后续联系起来

Magdalena Gabig-Cimińska1

  • 1Department of Medical Biology and Genetics, Faculty of Biology, University of Gdańsk, Gdańsk, Poland.

Frontiers in immunology
|December 15, 2025
PubMed
概括

SARS-CoV-2 破坏了自-溶酶体通路 (ALP),阻碍病毒清除并引起炎症. 恢复TFEB活动和ALP可能会对抗病毒持久性和长期COVID症状.

关键词:
在 COVID-19 疫情中,长时间的COVID.这就是SARS-CoV-2病毒.自-溶酶体通路 (ALP) 是一种自-溶酶体通路.主体导向疗法 主体导向疗法溶酶体内有机细胞转录因子EB (TFEB) 转录因子EB

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