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抑郁症患者对突然引入的听觉干扰产生更大的适应性和纠正性反应
Alexis Basciano1, Sara-Ching Chao1, Amy Gomez1
1College of Health Solutions, Arizona State University, Tempe, AZ, United States.
Frontiers in human neuroscience
|December 15, 2025
概括
患有失言症 (PWA) 的人表现出言语运动控制的改变,但响应因扰乱时间表而异. 突然的听觉反变化改善了PWA的适应和纠正能力,表明更好的错误检测和代理.
科学领域:
- 语音语言病理学 语言病理学
- 听觉电机控制器的控制器
- 神经科学是一个神经科学.
背景情况:
- 患有失言症 (PWA) 的人表现出改变的语音运动控制,影响反和前系统.
- 在PWA中,扰动时间表对这些语音子系统的差异性影响仍未得到充分研究.
研究的目的:
- 为了研究PWA在逐渐和突然的听觉扰乱计划下听觉运动适应和纠正反应的程度.
- 为了在不同的扰乱条件下比较PWA和神经典型成年人 (NT) 之间的语音运动控制反应.
主要方法:
- 9名PWA和12名NT成年人参与了逐渐和突然改变的听觉反 (AAF) 范式.
- 适应性反应 (feedforward) 被测量为语音产生的前100 ms中的形式变化.
- 纠正反应 (反) 由后期 (200-300毫秒) 和早期 (0-100毫秒) 语音部分之间的差异计算出来.
主要成果:
- 观察到群体 (PWA与NT) 和扰动时间表之间的显著相互作用.
- PWA的适应性和纠正性反应与突然扰乱计划下的NT成年人更相似.
- 个别分析揭示了PWA在逐渐和突然AAF范式的适应和纠正反应中明显的损伤模式.
结论:
- 使用适应范式在PWA中测量适应和纠正反应是可行的和有信息的.
- 根据扰乱时间表,PWA在适应性和纠正性语音运动控制中表现出差异性损伤.
- 突然的干扰可能会增强PWA的适应和纠正能力,可能是通过改善听觉错误检测和对语音产生代理的感觉.
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