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Updated: Jan 8, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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NLRP3炎症酶激活调节中性粒细胞外细胞陷的形成,并加剧支气管支气管炎症

Zhao-Ming Chen1, Jia-Hui He1,2, Rui-di Tang1,3

  • 1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Joint International Research Laboratory of Respiratory Health, Guangdong Basic Research Center of Excellence for Respiratory Medicine, Department of Allergy and Clinical Immunology, Department of Respiratory and Critical Care Medicine, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510163, P. R. China.

Research (Washington, D.C.)
|December 15, 2025
PubMed
概括

核酸结合寡聚化域类受体蛋白3 (NLRP3) 炎症酶激活促进中性粒细胞外细胞陷 (NET) 在支气管切除症中的形成. 这加剧了呼吸道炎症和上皮损伤,突出了NLRP3作为治疗点.

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