在患有中性粒细胞-淋巴细胞比率的儿童中诊断急性尾炎:一个横截面研究
Mohamed Mahmoud Shalaby1, Ahmed Alawi2, Bayan Mohammed Fatani3
1Pediatric Surgery Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Frontiers in pediatrics
|December 15, 2025
概括
中性粒细胞与淋巴细胞的比率 (NLR) 可以帮助诊断急性尾炎 (AA) 和儿童复杂尾炎. 这种具有成本效益的标志物在儿科患者中显示出显著的关联.
科学领域:
- 儿科手术 儿科手术
- 血液学 血液学 血液学
- 诊断标记器 诊断标记器
背景情况:
- 在儿童中诊断急性尾炎 (AA) 由于异型症状而带来挑战.
- 非典型的表现可以使儿科患者的准确和及时诊断复杂化.
研究的目的:
- 评估儿童急性尾炎中中性粒细胞与淋巴细胞比率 (NLR) 的诊断价值.
- 确定NLR是否可以作为诊断AA和儿童复杂尾炎的辅助标记.
主要方法:
- 对200名接受尾切除术的儿科患者 (0-14岁) 进行了回顾性横截面研究.
- 患者被分为正常尾 (n=32),急性尾炎 (n=133) 和穿孔尾炎 (n=35) 组.
- 对白细胞计数,中性粒细胞计数和与手术发现相关的NLR进行分析.
主要成果:
- 中性细胞与淋巴细胞的比率 (NLR),白细胞计数 (WBC) 和中性细胞计数在尾炎组显著增加.
- 多变量回归确认的NLR和WBC计数与AA相关 (P≤0.001).
- NLR与复杂尾炎 (P=0.012) 有着显著的关联,在定义的切断点上具有特定的敏感性和特异性.
结论:
- 中性粒细胞与淋巴细胞比率 (NLR) 是儿科急性尾炎的潜在有用的辅助诊断标志物.
- NLR提供了一种具有成本效益的方法来帮助儿童诊断简单和复杂的尾炎.
- 这项研究支持NLR作为儿童尾炎诊断途径中宝贵的工具的实用性.
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