使用经典机器学习模型进行基于语音的糖尿病前期预测
Jessica Oreskovic1, Ghazal Fazli2, Vanita Varma3
1Klick Applied Sciences, Klick, Inc., Toronto, ON, Canada.
Frontiers in clinical diabetes and healthcare
|December 15, 2025
概括
语音分析显示了查糖尿病前期的潜力,但模型难以在不同人群中概括. 需要对各种数据进行进一步的研究,以便在现实世界中应用.
科学领域:
- 生物医学工程 生物医学工程
- 计算生物学 计算生物学
- 代谢性疾病研究研究
背景情况:
- 糖尿病前期是一种常见的疾病,增加了2型糖尿病和心血管疾病的风险.
- 超过80%的糖尿病前期患者仍未被诊断出来,这突显了公共卫生领域的严重差距.
- 语音分析提供了一种非侵入性查方法,先前成功检测高血压和2型糖尿病.
研究的目的:
- 研究基于语音的机器学习模型在识别糖尿病前期患者的有效性.
- 评估这些基于语音的模型在不同人群中的通用性.
主要方法:
- 来自印度和加拿大的参与者通过移动应用程序提供语音录音;通过HbA1c评估血糖状况.
- 从语音样本中提取了167个声学特征,并开发了性别特定的机器学习模型.
- 模型使用L1-规范化后勤回归 (LASSO) 进行特征选择和SMOTE用于类失衡,并通过交叉验证和持久测试进行评估.
主要成果:
- 在交叉验证中,最佳女性模型获得了0.78平衡精度,最佳男性模型获得了0.68.
- 坚持测试显示,在不平衡的数据集上训练的男性XGBoost模型比交叉验证模型更好地概括.
- 模型在独立的加拿大数据集上表现出不良的概括性,其中一些无法准确识别糖尿病前参与者.
结论:
- 基于语音的模型在受控环境中显示出预糖尿病查的前景.
- 当在不同的地理或人口群体中应用时,模型性能显著下降.
- 开发更强大,更适用的选工具需要多样化的培训数据和特定人群的模型调整.
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