将甲状腺功能与身体组成相结合:布里奇比率和心血管风险 - - 一项试点研究
Çağlar Kaya1, Servet Altay1, Meral Kayıkçıoğlu2
1Department of Cardiology, Faculty of Medicine, Trakya University, Edirne, Türkiye.
身体圆度指数 (BRI) 和新的BRI/TSH比率 (BRITSH) 可以帮助预测冠状动脉疾病 (CAD) 在患有甲状腺功能低下症的患者. 这些简单的措施可以改善对甲状腺功能低下个体的心血管风险评估.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
背景情况:
- 甲状腺功能低下是心血管疾病的重要危险因素,影响脂质谱,胰岛素耐药性和内脏脂肪.
- 现有的风险评估工具可能无法完全捕捉甲状腺功能低下患者的心血管风险.
研究的目的:
- 评估冠状动脉疾病 (CAD) 的身体圆度指数 (BRI) 的预测值.
- 评估一种新的BRI/TSH比率 (BRITSH) 在确定甲状腺功能低下患者的CAD的诊断性能.
主要方法:
- 一项涉及152名甲状腺功能低下患者 (55名患有CAD,97名对照) 的横截面研究.
- 数据包括BRI,TSH水平,脂质概况和其他临床参数.
- 采用了接收器操作特征 (ROC) 曲线分析和后勤回归.
主要成果:
- 在CAD组中观察到较高的BRI值和较低的BRITSH比率.
- BRI显示出强大的预测值 (AUC=0.86),而BRITSH显示出中等能力 (AUC=0.67).
- 英国人,年龄,糖尿病,hs-CRP和非HDL胆固醇是独立的CAD预测因素.
结论:
- 布里茨比率是一种新的,独立的预测器,用于预测甲状腺功能低下患者的CAD.
- "一带一路"还显示出在识别CAD风险方面具有很好的潜力.
- 这些简单的指标可以在常规的临床实践中提高心血管风险评估,以治疗甲状腺功能低下症.
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