艾滋病毒诊断和预暴露预防 (PrEP) 处方在双相情感障碍的商业保险人员中
Samuel R Bunting1,2, Max J Hyman3, Aniruddha Hazra4
1Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois.
The Journal of clinical psychiatry
|December 15, 2025
概括
在双相情感障碍 (BD) 患者中,用于预防艾滋病毒的PrEP使用率极低,不到1%的人被处方这种药物. 将PrEP服务整合到精神病护理中对于增加吸收和打击艾滋病毒流行病至关重要.
科学领域:
- 公共卫生 公共卫生
- 心理健康 心理健康
- 预防传染病 预防传染病
背景情况:
- 双极性障碍 (BD) 是一种慢性精神疾病,与艾滋病毒感染风险增加有关.
- 暴露前预防 (PrEP) 是一种高效的艾滋病毒预防方法,但其在BD患者中的使用尚未得到充分理解.
研究的目的:
- 研究在被诊断患有双相情感障碍的人群中使用PrEP预防艾滋病毒.
- 在这个人群中确定与艾滋病毒诊断和PrEP处方相关的因素.
主要方法:
- 使用Merative MarketScan索赔数据库 (2010-2022) 进行了一项回顾性队列研究.
- 该研究确定了BD的个体,并分析了性传播感染 (STIs),精神病医院住院和医疗保健接触的数据.
- 关键结果包括新的艾滋病毒诊断和PrEP处方率.
主要成果:
- 该队列包括333,867名患有BD的个人. 艾滋病毒诊断在男性和伴随性兴奋剂使用障碍患者中更为普遍.
- 只有1337名BD患者 (不到1%) 服用了PrEP,其中909人至少服用了3个月.
- 在多次感染性传染病的人群中,不到4%的人接受了PrEP,尽管这是一个指示.
结论:
- 在BD的商业保险人群中,PrEP的使用率非常低,这凸显了艾滋病毒预防方面的重大差距.
- 将PrEP处方纳入常规精神病治疗中可能是一个有效的策略,以增加其使用.
- 加强对PrEP护理连续性的参与对于结束艾滋病毒大流行至关重要,特别是对于那些患有BD的弱势群体.
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