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miR-103a通过直接向OGG1来调节氧化应激下人类星体细胞的DNA修复能力

Chukwumaobim D O Nwokwu1, Gergana G Nestorova2, Malik H Walker3

  • 1Department of Chemistry and Physics, Florida Gulf Coast University, Fort Myers, FL, USA. cnwokwu@fgcu.edu.

Molecular biology reports
|December 15, 2025
PubMed
概括

微RNA-103a直接调节8-oxoguanine glycosylase 1 (OGG1),这是一个关键的DNA修复酶. 这一发现揭示了细胞应激反应的新机制,并为神经系统疾病提供了潜在的治疗点.

关键词:
修复DNA的修复DNA的修复这是一个微型RNA.神经退行发生神经退行.其他 OGG1氧化应激是一种氧化应激.治疗目标 治疗目标

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