在维护血液透析患者中开发和验证用于预测腹腔大动脉化的诺米克图
Miao Yu1, Xiaoyan Bao1, Xinfeng Qian2
1Hemodialysis Center of Affiliated Hospital of Jiangnan University, Hefeng Road 1000 #, Wuxi, 214000, JiangSu, China.
International urology and nephrology
|December 15, 2025
概括
一种新的诺米图准确地预测了维护血液透析 (MHD) 患者的腹腔大动脉化 (AAC). 这种工具有助于临床医生识别AAC高风险个体,促进早期干预.
科学领域:
- 科和心血管健康
- 医学成像和诊断 医学成像和诊断
- 生物统计学和预测建模
背景情况:
- 腹腔大动脉化 (AAC) 是接受维持血液透析 (MHD) 的患者常见的并发症.
- 早期识别AAC风险因素对于管理MHD患者心血管并发症至关重要.
- 在MHD群体中AAC的现有预测工具是有限的.
研究的目的:
- 开发和验证一个名图,用于预测维护血液透析 (MHD) 患者的腹腔大动脉化 (AAC).
- 为MHD患者提供AAC发生的视觉预测评估工具.
- 帮助临床医生早期识别AAC.高风险人群.
主要方法:
- 对334名患有MHD的末期病患者进行了回顾性横截面研究.
- 患者被分为训练 (n=200) 和验证 (n=134) 队列.
- 后勤回归分析确定了独立的风险因素;使用AUC和Hosmer-Lemeshow测试构建和验证了一个名图.
主要成果:
- 在研究人群中,AAC的发病率为71.0%.
- 确定了六个AAC的独立风险因素:年龄,透析年份,hs-CRP,,iPTH和25(OH) D.
- 诺米图表显示出强大的预测准确性,AUC为0.918 (训练) 和0.826 (验证).
结论:
- 已经成功开发和验证了用于预测MHD患者AAC的易于使用的nomogram.
- 该名录有效地识别了AAC.高风险个体.
- 这种工具可以帮助临床管理和MHD患者在AAC方面的风险分层.
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