弥合差距:在急性冠状动脉综合征中探索右心室 - 肺动脉合 - 一项试点研究
Linda Piras1, Nicola Tartaglia2, Giuliano Tocci2
1Clinical and Molecular Medicine Department, Sapienza University of Rome, Rome, Italy. linda.piras@uniroma1.it.
概括
评估右心室-肺动脉合的TAPSE/PASP比率与急性冠状动脉综合征 (ACS) 患者的主要不良心血管事件和更长的住院时间有关. 然而,它不能独立预测多变量分析的结果.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 急性冠状动脉综合征是什么
背景情况:
- 右心室 - 肺动脉 (RV-PA) 合评估了RV功能和后负载之间的平衡.
- 损坏的合,以低TAPSE/PASP比率表示,与各种疾病的预后不佳有关.
- 在急性冠状动脉综合征 (ACS) 中,RV-PA合的预后作用仍然不清楚.
研究的目的:
- 为了评估TAPSE/PASP比率在ACS患者的住院预后意义.
- 在这个人群中确定低TAPSE/PASP比率的预测因素.
主要方法:
- 一项对152名ACS患者 (STEMI/NSTEMI) 的回顾性试点研究,具有可用的心声TAPSE/PASP数据.
- 评估了TAPSE/PASP比率与住院主要不良心血管事件 (MACE),心室节律失常,血栓形成和长时间住院的相关性.
- 确定了低TAPSE/PASP比率的预测因素.
主要成果:
- 在单变量分析中,TAPSE/PASP比率<0.55与MACE和长时间住院有关.
- 在多变量分析中,这种关联并不显著.
- 低TAPSE/PASP的预测是E/e'>14,右心室卷入和年龄>75岁.
结论:
- 低RV-PA合 (TAPSE/PASP<0.55) 与ACS.的不良住院结果有关.
- 在ACS患者的多变量分析中,TAPSE/PASP比率缺乏独立的预后价值.
- 在ACS中,E/e'比率,RV参与度和晚年是受损RV-PA合的关键预测因素.
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